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What is Sildenafil?
Sildenafil is an active substance Viagra is composed of. This name is familiar to many men either through hearsay or firsthand. Viagra has proved to be the most effective medicine not only for male impotence but also for pulmonary arterial hypertension (Revatio). A patient can be prescribed Sildenafil even if he has diabetes. The medicine has been manufactured by Pfizer since 1998.
Mechanism of Action
The key role in the Sildenafil mechanism of action belongs to a special enzyme that is inhibited by Sldenafil. As a result, a patient has stable blood flow to genital area, which allows of a stable erection.
How Do Pills Look Like?
Sildenafil Generic pills are easy to recognize. The color of a pill is blue. A pill has the shape of a diamond. The manufacturer has decided to leave a trace by engraving “Pfizer” on one side of a pill. On the other side there is вЂњVGR XXвЂќ where possible weight values can be put instead of XX. Possible weight values are 25, 50 and 100 mg. You should know this information if you intend to use Sildenafil.
How to Take Sildenafil?
Before you use Sildenafil it is vitally important to follow the dosing schedule and dosage recommendations given by your doctor. Any deviation can result in serious adverse effects.
The most important thing is that you should take only one pill within 24 hours. It is recommended that you take your dose half an hour before a planned sexual activity.
If you use Sildenafil (Revatio) for treating pulmonary arterial hypertension, your recommended dose schedule is 3 times a day.
Sildenafil: Side Effects
Numerous clinical trials revealed common adverse effects that Sildenafil may bring on. First of all, a patient may develop a headache, sudden flushing, runny nose and dyspepsia. Impaired vision as well as impaired hearing is also possible. Vision changes may include blurred vision and photophobia (hypersensitivity to visible light that causes pain). Other vision symptoms may include cyanopsia (when a person sees everything blue colored around him), loss of peripheral vision and blurriness. However, vision changes are rather a rare phenomenon in Sildenafil patients.
Sildenafil misuse or individual intolerance may lead to serious adverse effects that are, however, uncommon. Priapism are among them. It’s a serious medical condition when penis remains erect for more than the Sildenafil effect is supposed to endure вЂ“ for more than 4 hours. Priapism requires immediate emergency medical attention. Aged patients should be especially careful when taking Sildenafil as they are faced with the risk of developing sudden heart attack. Sudden hearing loss, severe hypotension, stroke and some other symptoms are also possible. Before you use Sildenafil, your doctor should specify a list of possible adverse effects.
Sildenafil: Drug Interactions
There is a list of drugs and substances that may form undesirable drug interactions with Sildenafil:
- protease inhibitors (used for treating HIV);
- alpha blockers.
If you use any of these drugs concomitantly with Sildenafil, inform your doctor so that he can conclude whether you can continue such joint treatment or not.
- if a patient is taking nitate/nitrite-containing drugs;
- in men at heart attack risk;
- in patients with impaired liver or/and kidney function;
- in men with hypotension;
- in patients who have recently had heart attack or stroke;
- in patients with hereditary retinal disorders.