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Sertraline is one of the most prescribed antidepressants belonging to SSRIs, or selective serotonin reuptake inhibitors.

Sertraline: Drug description
The drug contains active ingredient sertraline that works by blocking chemicals that cause panic, anxiety and other symptoms of depression.

Sertraline: Indications
Doctors usually recommend patients to use Sertraline to treat these disorders:

  • Depression
  • Anxiety disorders (psychiatric disorders characterized by worrying, rumination, and uneasiness)
  • Obsessive-compulsive disorder
  • Panic disorder (anxiety disorder characterized by regular panic attacks)
  • Premenstrual dysphoric disorder (PMDD)
  • Post-traumatic stress disorder

Your doctor may tell you use sertraline to treat some other disorders not indicated in this list.

Sertraline: Dosage
You may take Sertraline tablets with or without food. Dilute the liquid form of the drug before you take it. Take the drug at the same time.

If you use Sertraline, follow the directions on the information leaflet that comes with the drug. Do not stop using the drug suddenly, as you may develop unwanted symptoms. Do not change the dosage without consulting your doctor.

The dosage depends on the exact type of disorder you are treating. These are the standard recommended dosages:

  • Major Depressive Disorder: 50mg once daily
  • Panic Disorder: 25 mg once daily
  • Posttraumatic Stress Disorder: 25 mg once daily
  • Anxiety Disorder: 25 mg once daily. The dose is increased to 50 mg starting from the second week.
  • Obsessive-Compulsive Disorder: 50mg once daily
  • Premenstrual Dysphoric Disorder: 50mg once daily

If you do not respond to a 25 mg dose, the dosage may be increased to 50mg. The dosage may be changed in patients with other severe conditions.

Sertraline: Precautions
Do not use Sertraline if you have allergic reaction to its components, especially to sertraline. Read the information leaflet to find a complete list of the drug’s ingredients.

You can use Sertraline, but it is recommended to tell your doctor if you have epilepsy, seizures, liver disease, kidney disease, blood clotting problems, bipolar disorder, drug abuse, or other severe condition.

Avoid alcohol when taking Sertraline as it increases the risk of side effects.

Avoid driving a car when using Sertraline as it may relax your attention.

You may have suicidal thoughts when you first use Sertraline, especially if you are under twenty four years of age. Tell your doctor if you have ever had suicidal thoughts before.

To ensure that Sertraline is a right drug for you, read the information leaflet carefully.

Sertraline: Drug Interaction
Tell your doctor if you are taking any drugs, herbs, or vitamins, as a drug interaction may occur. Sertraline should not be used together with these drugs:

  • Pimozide
  • Cimetidine
  • Digitoxin
  • Fentanyl
  • Blood thinners (warfarin)
  • Other antidepressant (amitriptyline, bupropion, citalopram, desvenlafaxine, duloxetine, fluoxetine, fluvoxamine, nortriptyline)
  • Heart rhythm medication (flecainide, propafenone)
  • Migraine medicines (almotriptan, frovatriptan, rizatriptan, zolmitriptan)
  • Methylene blue injection
  • MAO inhibitor (isocarboxazid, phenelzine, linezolid, selegiline, rasagiline, tranylcypromine)
  • Nonsteroidal anti-inflammatory drug, NSAIDs (aspirin, ibuprofen, naproxen, celecoxib, diclofenac, indomethacin).
  • These drugs together with Sertraline may make you bleed easily.
  • Sedatives, sleeping pills, opioid pain medicine, muscle relaxers, medicines for seizures. These drugs together with Sertraline may make you too sleepy.

Sertraline: Side effects
As any other drug, Sertraline may sometimes cause unwanted side effects.The most common include decreased sexual ability and failure to reach an orgasm. Less common side effects include confusion, diarrhea, convulsions, irregular heartbeat, drowsiness, fever, hives, and others.

To eliminate the risk of developing side effects, follow safety precautions connected with Sertraline usage and keep the prescribed dosage.

Sertraline: Storage
Keep Sertraline away from heat at room temperature.

Sertraline: Missing a dose/overdose
If you missed the dose, take the missed dose as soon as you remember unless it is time for the next one.

Seek medical help if you overdose. Possible signs of an overdose include dizziness, nausea and vomiting, tremor, seizures.

Sertraline: How Supplied
Sertraline is available as capsular-shaped tablets (containing 25, 50 and 100mg of active component) and oral concentrate (containing 20mg of active component per mL).

Sertraline: Where to buy
Sertraline is not available over-the-counter, but you can find Sertraline in the internet. Online pharmacies offer generic Sertraline and bulk discounts for the clients. Ordering procedure is fast and simple as never before.